1. Irma's practical skills and world knowledge seem so limited, even compared to those of her brother Carlo. What abilities and traits help her navigate the difficult passages from Opi to Naples and then west?

2. Irma's mother devoutly believes that "If you leave Opi, you will die with strangers." How does this assertion shape Irma's experience and how does she ultimately refine it in a way that allows her to move forward in her journey? How does this family assertion compare to others you may have encountered?

3. Opi, real and remembered, is a powerful force for Irma's self-image and world-view. How does her conception of Opi change through the novel?

4. Unlike many fictional heroines and perhaps many young women, Irma initially has little interest in a romantic union. Why not and what must change for her to have a satisfying intimate relationship?

5. At various times in her journey, Irma makes choices which she herself feels are at odds with the Irma Vitale that she "really is." Is she accurate in this assessment?

6. Irma Vitale is surrounded by immigrants as she makes her passage west. What various ways of relating to "the Old Country" are represented by these other immigrants, her "fellow strangers"?

7. Sofia gives Irma the option to leave Jake and Daisy's flat. Yet Irma stays. How does this choice reflect her course since first encountering Jake?

8. Irma's profession evolves from needle worker to dressmaker and finally surgeon. What inner changes parallel this evolution?

9. Today, as in Irma's time, many people live far from their birthplace for a variety of reasons. What pressures, challenges and supports seem universal about her experience?